Nasal interferon responses in leukaemia

Arch Dis Child. 1985 Sep;60(9):829-31. doi: 10.1136/adc.60.9.829.

Abstract

Nasal concentrations of leucocyte interferon measured immunoradiometrically were appreciably higher in children infected with influenza viruses than those infected with paramyxoviruses. Regardless of the infecting virus, leukaemic children produced normal amounts of interferon, but this appeared to have little effect on the duration of excretion of virus.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Humans
  • Infant
  • Interferon Type I / biosynthesis*
  • Leukemia, Lymphoid / complications
  • Leukemia, Lymphoid / metabolism*
  • Nasal Mucosa / metabolism
  • Respiratory Tract Infections / complications
  • Respiratory Tract Infections / metabolism*
  • Virus Diseases / complications
  • Virus Diseases / metabolism*

Substances

  • Interferon Type I