Editorial Commentary: Biologic Augmentation of Rotator Cuff Repair: Platelet-Rich Plasma May Be of Significant Benefit, Whereas Atelocollagen Cannot Be Recommended

Arthroscopy. 2024 Apr 16:S0749-8063(24)00273-1. doi: 10.1016/j.arthro.2024.04.005. Online ahead of print.


The field of orthobiologics continues to advance at a rapid pace and theoretically holds some promise to augment the biologic healing response in rotator cuff repair (RCR). However, the clinical evidence for use of substances such as platelet-rich plasma (PRP) for RCR remains inconclusive. Atelocollagen, as a synthetic collagen substitute, has been proposed as another alternative to provide more collagen substrate for healing, but outcomes data with this technique is lacking. In contrast, (biologic) PRP has been well studied, does not show adverse outcomes, and has been shown to improve healing of large to massive tears, as well as RCR outcomes. As biologic augmentation options continue to push the envelope on indications, due diligence is required to carefully examine options for safety and efficacy. Evolutions in RCR should also continue to motivate sports medicine surgeons and researchers to seek out further innovations to improve patient outcomes. That said, PRP outcome improvement for RCR is not definitive and requires further study. RCR can humble even the best of surgeons and demands that we continue to look for ways to improve outcomes.

Publication types

  • Editorial