Olfactory Neuroblastoma Causing Cushing's Syndrome Due to the Ectopic Adrenocorticotropic Hormone (ACTH) Secretion: A Case Report

Abdulrahman A Alsarari; Anas A Abdulkader; Waqar A Farooqi; Salwa K Al-Shibani; Tarig S Al Khuwaitir

doi:10.7759/cureus.56434

Olfactory Neuroblastoma Causing Cushing's Syndrome Due to the Ectopic Adrenocorticotropic Hormone (ACTH) Secretion: A Case Report

Cureus. 2024 Mar 19;16(3):e56434. doi: 10.7759/cureus.56434. eCollection 2024 Mar.

Authors

Abdulrahman A Alsarari¹, Anas A Abdulkader¹, Waqar A Farooqi², Salwa K Al-Shibani³, Tarig S Al Khuwaitir⁴

Affiliations

¹ Medicine and Surgery, Al Maarefa University, Riyadh, SAU.
² Internal Medicine, Al Maarefa University, Riyadh, SAU.
³ Anatomic Pathology, Ad-Diriyah Hospital, Ministry of Health, Riyadh, SAU.
⁴ Internal Medicine, King Saud Medical City, Riyadh, SAU.

Abstract

Cushing's syndrome is a constellation of features occurring due to high blood cortisol levels. We report a case of a 47-year-old male with a history of recurrent olfactory neuroblastoma (ONB). He presented with bilateral lower limb weakness and anosmia and was found to have Cushing's syndrome due to high adrenocorticotropic hormone (ACTH) levels from an ectopic source, ONB in this case. Serum cortisol and ACTH levels declined after tumor removal.

Keywords: case report; cushing’s syndrome; ectopic acth syndrome (eas); hypokalemia; olfactory neuroblastoma.

Publication types

Case Reports