Rapid molecular epidemiology investigations into two recent measles outbreaks in Israel detected from October 2023 to January 2024

Euro Surveill. 2024 Apr;29(16):2400202. doi: 10.2807/1560-7917.ES.2024.29.16.2400202.

Abstract

Between late 2023 and early 2024, two measles outbreaks occurred in Israel, each caused by importation of measles virus strains of respective B3 and D8 genotypes. In this study, we validate transmission pathways uncovered by epidemiological investigations using a rapid molecular approach, based on complete measles virus genomes. The presented findings support this rapid molecular approach in complementing conventional contact tracing and highlight its potential for informing public health interventions.

Keywords: Measles; Molecular epidemiology; Whole Genome Sequencing (WGS).

MeSH terms

  • Disease Outbreaks
  • Genotype
  • Humans
  • Israel / epidemiology
  • Measles virus / genetics
  • Measles* / diagnosis
  • Measles* / epidemiology
  • Molecular Epidemiology
  • Phylogeny
  • Sequence Analysis, DNA