Imaging Findings of Calcifying Nested Stromal-Epithelial Tumour of the Liver: A Case Report and Literature Review

Ermin Cai; Yiheng Zheng; Mingliang Wang; Mengsu Zeng

doi:10.2174/0115734056291871240327041053

Imaging Findings of Calcifying Nested Stromal-Epithelial Tumour of the Liver: A Case Report and Literature Review

Curr Med Imaging. 2024 Apr 18. doi: 10.2174/0115734056291871240327041053. Online ahead of print.

Authors

Ermin Cai¹, Yiheng Zheng¹, Mingliang Wang^{2

3}, Mengsu Zeng^{2

3}

Affiliations

¹ Department of Radiology, Zhuji People's Hospital, Shaoxing 311800, China.
² Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Medical Imaging, Shanghai 200032, China.
³ Department of Medical Imaging, Shanghai Medical College, Fudan University, Shanghai 200032, China.

PMID: 38639283
DOI: 10.2174/0115734056291871240327041053

Abstract

Background: A calcifying nested stromal-epithelial tumour (CNSET) is an erratic primary liver malignant tumour frequently discovered in young girls and females. Neither its pathogenesis nor its nosogenesis is clearly known. While principally indolent, infrequent tumours with aggressive clinical progression have been defined. This paper describes a CNSET case with rare clinical and imaging features.

Case presentation: A 17-year-old girl initially presented with enlarged lymph nodes near the main portal vein of the liver and a large liver tumour. Lesions were identified on the imaging findings obtained via positron emission tomography-computed tomography (CT) scanning, including an abnormal increase of heterogeneous glucose metabolism in the intrahepatic mass, with a maximum standardised uptake value of around 3.2. The CT imaging showed multiple dense shadows in the lesion, while the magnetic resonance imaging indicated a long T1 and a slightly longer T2.

Conclusions: This study summarises the imaging features of CNSETs to provide a reference for diagnosing liver tumours. In addition, the literature on the topics covered was systematically reviewed.

Keywords: Calcifying nested stromal-epithelial tumours; computed tomography; differential diagnosis; nuclear magnetic resonance imaging; positron emission tomography/ computed tomography.

Publication types

Case Reports