Fever and Rash

Emerg Med Clin North Am. 2024 May;42(2):303-334. doi: 10.1016/j.emc.2024.01.005. Epub 2024 Mar 7.

Abstract

Infectious causes of fever and rash pose a diagnostic challenge for the emergency provider. It is often difficult to discern rashes associated with rapidly progressive and life-threatening infections from benign exanthems, which comprise the majority of rashes seen in the emergency department. Physicians must also consider serious noninfectious causes of fever and rash. A correct diagnosis depends on an exhaustive history and head-to-toe skin examination as most emergent causes of fever and rash remain clinical diagnoses. A provisional diagnosis and immediate treatment with antimicrobials and supportive care are usually required prior to the return of confirmatory laboratory testing.

Keywords: Arbovirus; Emergency medicine; Exanthem; Fever; Meningococcemia; Rash; Rocky Mountain spotted fever; Toxic shock syndrome.

Publication types

  • Review

MeSH terms

  • Exanthema* / complications
  • Exanthema* / etiology
  • Fever / diagnosis
  • Fever / etiology
  • Humans
  • Rocky Mountain Spotted Fever* / diagnosis
  • Rocky Mountain Spotted Fever* / drug therapy