Long-term risk of serious infections and mortality among patients surviving drug use-associated infective endocarditis

Clin Infect Dis. 2024 Apr 20:ciae214. doi: 10.1093/cid/ciae214. Online ahead of print.


Among a statewide cohort of 1,874 patients surviving hospitalization for drug use-associated endocarditis during 2017-2020, the 3-year risk of death or future hospitalization was 38% (16% for death prior to later infection, 14% for recurrent endocarditis, 14% for soft-tissue, 9% for bacteremia, 5% for bone/joint, and 4% for spinal infections).

Keywords: bacterial infections; endocarditis; injection drug use; mortality.