Transcatheter Edge-to-Edge Mitral Valve Repair in a Patient With Anderson-Fabry Disease

Mohamed Elwashahy; Jason Sharp; Dennis Wang; Tuan Nguyen-Dang; Jorge Moragues; Edward J F Danson

doi:10.1016/j.jaccas.2024.102271

Transcatheter Edge-to-Edge Mitral Valve Repair in a Patient With Anderson-Fabry Disease

JACC Case Rep. 2024 Feb 22;29(7):102271. doi: 10.1016/j.jaccas.2024.102271. eCollection 2024 Apr 3.

Authors

Mohamed Elwashahy¹, Jason Sharp², Dennis Wang², Tuan Nguyen-Dang¹, Jorge Moragues¹, Edward J F Danson^{1

2}

Affiliations

¹ Department of Cardiology, The Wollongong Hospital, Wollongong, New South Wales, Australia.
² Sydney Adventist Hospital, Wahroonga, New South Wales, Australia.

Abstract

Severe degenerative mitral regurgitation (DMR) is one cardiac manifestation of the multiorgan metabolic enzyme disorder Anderson-Fabry Disease (AFD). Although DMR is normally managed surgically, many patients with AFD are unsuitable for this. We present the first case of mitral transcatheter edge-to-edge repair in a patient with AFD.

Keywords: MitraClip; cardiomyocytes; heart failure; mitral regurgitation.

Publication types

Case Reports