Case of eccrine chondroid syringoma of the upper lip

BMJ Case Rep. 2024 Apr 22;17(4):e254899. doi: 10.1136/bcr-2023-254899.

Abstract

Chondroid syringoma (CS) is a benign, slow-growing mixed tumour that arises from the sweat glands and usually presents in the head and neck area. Histopathological examination is important for proper diagnosis, as CS is often confused with epidermal cysts due to its rare presentation. This article presents a man in his 40s with a right upper lip mass that emerged 6 months prior to presentation. An intraoral surgical excision was performed and the histopathological analysis revealed solid epithelial cells that formed multiple, non-branching ducts lined by cuboidal epithelium. Cystic spaces were filled by heterogeneous eosinophilic material embedded in chondromyxoid stroma. Histopathology identified the lesion as an eccrine-variant CS. The patient recovered well.

Keywords: Dermatology; Head and neck cancer; Oral and maxillofacial surgery; Otolaryngology / ENT; Plastic and reconstructive surgery.

Publication types

  • Case Reports

MeSH terms

  • Adenoma, Pleomorphic* / diagnosis
  • Adenoma, Pleomorphic* / diagnostic imaging
  • Adenoma, Pleomorphic* / pathology
  • Adenoma, Pleomorphic* / surgery
  • Adult
  • Diagnosis, Differential
  • Eccrine Glands / pathology
  • Humans
  • Lip / pathology
  • Lip / surgery
  • Lip Neoplasms* / diagnosis
  • Lip Neoplasms* / pathology
  • Lip Neoplasms* / surgery
  • Male
  • Sweat Gland Neoplasms* / diagnosis
  • Sweat Gland Neoplasms* / pathology
  • Sweat Gland Neoplasms* / surgery