NASCI case of the month: desmoplakin cardiomyopathy masquerading as acute myocarditis

Prateek C Gowda; Alessio Gasperetti; Stefan L Zimmerman

doi:10.1007/s10554-024-03112-z

NASCI case of the month: desmoplakin cardiomyopathy masquerading as acute myocarditis

Int J Cardiovasc Imaging. 2024 Apr 23. doi: 10.1007/s10554-024-03112-z. Online ahead of print.

Authors

Prateek C Gowda¹, Alessio Gasperetti², Stefan L Zimmerman³

Affiliations

¹ The Johns Hopkins University School of Medicine, Baltimore, USA.
² Division of Cardiology, Department of Medicine, The Johns Hopkins Hospital, Baltimore, USA.
³ The Russel H. Morgan Department of Radiology and Radiological Sciences, The Johns Hopkins University School of Medicine, Halstead B180, 1800 Orleans Street, Baltimore, MD, 21287, USA. stefan.zimmerman@jhmi.edu.

PMID: 38652395
DOI: 10.1007/s10554-024-03112-z

Abstract

We present a case of a young patient with chest pain. Labs and cardiac imaging were suspicious for acute myocarditis. Genetic testing revealed a diagnosis of desmoplakin cardiomyopathy. Desmoplakin cardiomyopathy may be considered in patients with recurrent acute myocarditis or a family history of cardiac disease to avoid the potential for misdiagnosis.

Keywords: Arrhythmias; Cardiomyopathy; Genetics; Magnetic resonance imaging (MRI).