INTRAVITREAL DEXAMETHASONE FOR THE TREATMENT OF MACULAR EDEMA SECONDARY TO HYDROXYCHLOROQUINE TOXICITY

Retin Cases Brief Rep. 2024 May 1;18(3):346-350. doi: 10.1097/ICB.0000000000001388. Epub 2022 Nov 25.

Abstract

Purpose: Cystoid macular edema is a vision-threatening complication infrequently associated with hydroxychloroquine retinal toxicity. There are limited data on the best treatment for this pathology.

Methods: A retrospective case series is presented.

Results: In this series, we present three cases of cystoid macular edema in patients with diagnosed hydroxychloroquine maculopathy successfully treated with intravitreal dexamethasone implantation.

Conclusion: Minimal literature has been published regarding the best management of cystoid macular edema related to hydroxychloroquine toxicity. Our case series suggests a possible new agent in the treatment of this rare occurrence.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antirheumatic Agents* / administration & dosage
  • Antirheumatic Agents* / adverse effects
  • Dexamethasone* / administration & dosage
  • Dexamethasone* / therapeutic use
  • Female
  • Glucocorticoids* / administration & dosage
  • Humans
  • Hydroxychloroquine* / administration & dosage
  • Hydroxychloroquine* / adverse effects
  • Intravitreal Injections*
  • Macular Edema* / chemically induced
  • Macular Edema* / drug therapy
  • Male
  • Middle Aged
  • Retrospective Studies
  • Tomography, Optical Coherence
  • Visual Acuity

Substances

  • Hydroxychloroquine
  • Dexamethasone
  • Glucocorticoids
  • Antirheumatic Agents