From morbidity reduction to cost-effectiveness: Enhanced recovery after surgery (ERAS) society recommendations in minimal invasive liver surgery

Langenbecks Arch Surg. 2024 Apr 23;409(1):137. doi: 10.1007/s00423-024-03329-5.

Abstract

Purpose: Minimal-invasive liver surgery (MILS) reduces surgical trauma and is associated with fewer postoperative complications. To amplify these benefits, perioperative multimodal concepts like Enhanced Recovery after Surgery (ERAS), can play a crucial role. We aimed to evaluate the cost-effectiveness for MILS in an ERAS program, considering the necessary additional workforce and associated expenses.

Methods: A prospective observational study comparing surgical approach in patients within an ERAS program compared to standard care from 2018-2022 at the Charité - Universitätsmedizin Berlin. Cost data were provided by the medical controlling office. ERAS items were applied according to the ERAS society recommendations.

Results: 537 patients underwent liver surgery (46% laparoscopic, 26% robotic assisted, 28% open surgery) and 487 were managed by the ERAS protocol. Implementation of ERAS reduced overall postoperative complications in the MILS group (18% vs. 32%, p = 0.048). Complications greater than Clavien-Dindo grade II incurred the highest costs (€ 31,093) compared to minor (€ 17,510) and no complications (€13,893; p < 0.001). In the event of major complications, profit margins were reduced by a median of € 6,640.

Conclusions: Embracing the ERAS society recommendations in liver surgery leads to a significant reduction of complications. This outcome justifies the higher cost associated with a well-structured ERAS protocol, as it effectively offsets the expenses of complications.

Keywords: Complication Management; Cost Analysis; ERAS; Minimal Invasive Liver Surgery.

Publication types

  • Observational Study

MeSH terms

  • Aged
  • Cost-Benefit Analysis*
  • Enhanced Recovery After Surgery*
  • Female
  • Hepatectomy* / adverse effects
  • Hepatectomy* / economics
  • Humans
  • Laparoscopy / adverse effects
  • Laparoscopy / economics
  • Male
  • Middle Aged
  • Minimally Invasive Surgical Procedures* / economics
  • Postoperative Complications* / economics
  • Postoperative Complications* / prevention & control
  • Prospective Studies
  • Robotic Surgical Procedures / adverse effects
  • Robotic Surgical Procedures / economics