A rare case of extensive neurogenic heterotopic ossification: a case report

BMC Musculoskelet Disord. 2024 Apr 23;25(1):313. doi: 10.1186/s12891-024-07369-2.

Abstract

Introduction: Neurogenic Heterotopic ossification (NHO) is a potential sequalae and a detrimental complication following neurological insult. It is characterized by formation of localized gradually progressive, peri-articular lamellar bone formation in extra-skeletal tissues. We would like to report a rare case of heterotopic ossification involving all 4 limbs, in which we tried to restore joint mobility to improve his functional status so that he could perform his daily tasks.

Case presentation: We present a case of a 33-year-old bed ridden male, diagnosed with NHO involving all 4 limbs (bilateral hip, right knee, right shoulder, left elbow). The patient had a crippled posture, significant pain and impaired range of motion hampering movement of all four limbs which prevented him from lying down supine, sitting, walking and performing activities of daily living. After three surgeries, the patient achieved wheelchair mobilization and upright posture with the assistance of calipers.

Conclusion: The management of NHO requires a multidisciplinary approach involving orthopaedic surgeons, neurologists & rehabilitation specialists. Prognosis of NHO depends on factors such as extent of ossification, underlying neurological condition & patients overall health.

Keywords: Neurogenic heterotopic ossification; Spasticity; Spinal cord injury; Traumatic brain injury.

Publication types

  • Case Reports

MeSH terms

  • Activities of Daily Living
  • Adult
  • Humans
  • Male
  • Ossification, Heterotopic* / complications
  • Ossification, Heterotopic* / diagnosis
  • Ossification, Heterotopic* / diagnostic imaging
  • Ossification, Heterotopic* / surgery
  • Posture
  • Range of Motion, Articular
  • Treatment Outcome