Objective: To explore the feasibility of establishing combat readiness blood bank with low titer group O whole blood and group A plasma.
Methods: The Galileo automatic blood analyzer was used to detect the titers of IgM anti-A and anti-B antibodies in the samples of group O blood donors and IgM anti-B titer in the samples of group A blood donors. Group O blood donors with antibody titers below 128 were selected and included in the mobile blood bank for combat readiness, group A plasma with anti-B titer lower than 128 and group O whole blood with antibody titers below 128 were included in the combat readiness entity blood bank.
Results: A total of 1 452 group O blood donors were selected, and the anti-A/B antibody titers were detected. Both antibody titers were distributed below 512, and both peak values of sample distribution were at titer 4. The proportion of samples with titers>128 for both antibodies was relatively low. There was a significant positive correlation between the titers of the two antibodies (r =0.383), and the proportion of samples with IgM anti-A titer higher than IgM anti-B titer was relatively high. 1 335(91.94%) group O blood donors with IgM anti-A and anti-B antibody titers <128 could be included in the mobile blood bank. The anti-B titer of group A blood was detected in 512 cases and the results showed that as the antibody titer increased, the proportion of blood donors gradually decreased. 99.8% of group A blood donors had anti-B antibody titer less than 128, and only one case did not meet the inclusion criteria.
Conclusion: The proportion of group O blood donors whose whole blood meet the low antibody titer standard is high, and almost all plasma of group A blood donors meet the low titer standard, which improves the blood supply rate in emergencies.
题目: 基于低效价O型全血及A型血浆建立战备血库的可行性分析.
目的: 探索用低效价O型全血及A型血浆建立战备血库的可行性。.
方法: 应用Galileo全自动血型分析仪检测O型献血者样本的IgM抗A、抗B抗体效价和A型献血者样本的IgM抗B效价，选取抗A、抗B效价同时低于128的O型献血者纳入战备流动血库，抗B效价低于128的A型血浆和抗A、抗B效价同时低于128的O型全血纳入战备实体血库。.
结果: 共选取1 452个O型献血者，检测抗A/B抗体效价，两种抗体效价均分布于512以下，且样本分布峰值均处于效价4，两种抗体效价>128的样本比例均较低；两种抗体效价存在明显正相关（r =0.383），且IgM抗A效价高于IgM抗B效价的样本比例较高；同时满足IgM抗A和抗B抗体效价<128的献血者1 335人（91.94%），可纳入流动血库。检测512例A型献血者抗B效价，结果显示，随着抗体效价的增高，样本比例逐渐降低；抗B抗体效价<128的献血者占99.8%，仅有1例不符合纳入条件。.
结论: O型献血者全血符合低效价标准的比例较高，A型献血者血浆几乎均符合低效价标准，提高了突发情况下的血液供应率。.
Keywords: combat readiness blood bank; mobile blood bank; antibody titer; group O whole blood; group A plasma; IgM anti-A/B.