The primary stability of a cementless PEEK femoral component is sensitive to BMI: A population-based FE study

J Biomech. 2024 May:168:112061. doi: 10.1016/j.jbiomech.2024.112061. Epub 2024 Mar 24.


The use of polyetheretherketone (PEEK) for cementless femoral total knee arthroplasty (TKA) components is of interest due to several potential advantages, e.g. the use in patients with metal hypersensitivity. Additionally, the stiffness of PEEK closer resembles the stiffness of bone, and therefore, peri-prosthetic stress-shielding may be avoided. When introducing a new implant material for cementless TKA designs, it is important to study its effect on the primary fixation, which is required for the long-term fixation. Finite element (FE) studies can be used to study the effect of PEEK as implant material on the primary fixation, which may be dependent on patient factors such as age, gender and body weight index (BMI). Therefore, the research objectives of this study were to investigate the effect of PEEK vs cobalt-chrome (CoCr) and patient characteristics on the primary fixation of a cementless femoral component. 280 FE models of 70 femora were created with varying implant material and gait and squat activity. Overall, the PEEK models generated larger peak micromotions than the CoCr models. Distinct differences were seen in the micromotion distributions between the PEEK and CoCr models for both the gait and squat models. The micromotions of all femoral models significantly increased with BMI. Neither gender nor age of the patients had a significant effect on the micromotions. This population study gives insights into the primary fixation of a cementless femoral component in a cohort of FE models with varying implant material and patient characteristics.

Keywords: Cementless femoral knee component; Finite element simulation; Micromotion; Polyetheretherketone; Populationstudy; Total knee arthroplasty.

MeSH terms

  • Aged
  • Arthroplasty, Replacement, Knee / methods
  • Benzophenones*
  • Body Mass Index*
  • Female
  • Femur* / surgery
  • Finite Element Analysis*
  • Humans
  • Ketones*
  • Knee Prosthesis
  • Male
  • Middle Aged
  • Polyethylene Glycols*
  • Polymers*
  • Prosthesis Design