3D auto-segmentation of biliary structure of living liver donors using magnetic resonance cholangiopancreatography for enhanced preoperative planning

Int J Surg. 2024 Apr 1;110(4):1975-1982. doi: 10.1097/JS9.0000000000001067.

Abstract

Background: This study aimed to develop an automated segmentation system for biliary structures using a deep learning model, based on data from magnetic resonance cholangiopancreatography (MRCP).

Materials and methods: Living liver donors who underwent MRCP using the gradient and spin echo technique followed by three-dimensional modeling were eligible for this study. A three-dimensional residual U-Net model was implemented for the deep learning process. Data were divided into training and test sets at a 9:1 ratio. Performance was assessed using the dice similarity coefficient to compare the model's segmentation with the manually labeled ground truth.

Results: The study incorporated 250 cases. There was no difference in the baseline characteristics between the train set (n=225) and test set (n=25). The overall mean Dice Similarity Coefficient was 0.80±0.20 between the ground truth and inference result. The qualitative assessment of the model showed relatively high accuracy especially for the common bile duct (88%), common hepatic duct (92%), hilum (96%), right hepatic duct (100%), and left hepatic duct (96%), while the third-order branch of the right hepatic duct (18.2%) showed low accuracy.

Conclusion: The developed automated segmentation model for biliary structures, utilizing MRCP data and deep learning techniques, demonstrated robust performance and holds potential for further advancements in automation.

MeSH terms

  • Adult
  • Cholangiopancreatography, Magnetic Resonance* / methods
  • Deep Learning*
  • Female
  • Humans
  • Imaging, Three-Dimensional*
  • Liver / anatomy & histology
  • Liver / diagnostic imaging
  • Liver Transplantation*
  • Living Donors*
  • Male
  • Middle Aged
  • Preoperative Care / methods
  • Retrospective Studies