Concomitant ectopic Enterobius vermicularis infection in uterine cervical cancer

BMC Womens Health. 2024 Apr 27;24(1):265. doi: 10.1186/s12905-024-03073-4.

Abstract

Background: Enterobius vermicularis (E. vermicularis), also referred to as pinworm, is a widespread human intestinal parasite which predominantly occurs in young children, making their caretakers a population at risk for the transmission of this helminth. It can occasionally affect extraintestinal organs and tissues, including the female genital tract. Infestation can be asymptomatic or manifest as different kinds of gynaecological disorders, such as pelvic inflammation mimicking tumours, abnormal uterine bleeding, or vaginitis. Diagnosis is made by identifying ova in the sample collected from the perineal skin using a transparent adhesive tape or microscopic examination of resected tissue. Mebendazole is the first-line medication and should also be administered to all household members.

Case presentation: We present a case of a patient who had undergone surgery for invasive cervical cancer with an accidental finding of E. vermicularis eggs in the cervix.

Conclusions: Although not very common, infestation with E. vermicularis should be considered in differential diagnoses of various gynaecological disorders accompanied by histological findings of granulomatous inflammation.

Keywords: Enterobius vermicularis; Cervical cancer; Extraintestinal manifestation; Female genital tract; Uterine cervix.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Animals
  • Cervix Uteri / parasitology
  • Cervix Uteri / pathology
  • Diagnosis, Differential
  • Enterobiasis* / complications
  • Enterobiasis* / diagnosis
  • Enterobius* / isolation & purification
  • Female
  • Humans
  • Mebendazole / therapeutic use
  • Middle Aged
  • Uterine Cervical Neoplasms* / diagnosis
  • Uterine Cervical Neoplasms* / surgery

Substances

  • Mebendazole