Unveiling the Unlikely: Extraskeletal Ewing Sarcoma Masquerading as Gastrointestinal Bleeding

Cureus. 2024 Mar 28;16(3):e57109. doi: 10.7759/cureus.57109. eCollection 2024 Mar.

Abstract

While Ewing sarcoma is traditionally a malignant tumor of bone, it may uncommonly present extra-skeletally, leading to an array of puzzling presentations depending on the tissue involved. Here, we describe the case of a 66-year-old man who presented to the primary care office for evaluation of intermittent melena. He ultimately underwent capsule endoscopy and developed a secondary small bowel obstruction, unveiling his neoplasm. The tumor was then resected and managed with surveillance only, and the patient remains without evidence of disease after four years of follow-up.

Keywords: extraskeletal ewing sarcoma; extraskeletal ewing's sarcoma; iron deficiency anemia (ida); iron-refractory iron deficiency anemia; obscure gi bleed; small bowel tumor.

Publication types

  • Case Reports