Objective: Myocardial infarction, coronary heart disease is one of the serious types, come on urgent, case fatality rate is high, especially the front wall or extensive anterior wall myocardial infarction, easy to merge cardiac insufficiency, arrhythmia, even in patients with sudden death will happen, and life-threatening. The aim of this study was to investigate the effects of HOPE management mode on cardiac function, quality of life and in-hospital cardiovascular adverse events in patients with myocardial infarction.
Methods: 118 patients with myocardial infarction hospitalized in our hospital from January 2020 to March 2022 were randomly divided into study group (n=59) and control group (n=59) and carried out a prospective study. The study group was treated with HOPE management mode, the control group was treated with conventional intervention. The LVEF, GRACE, quality of life were evaluated before intervention, 1 week after, 1 month and 3 months after intervention to evaluate the improvement of clinical symptoms, cardiac function and quality of life of patients.
Results: The LVEF were increased from (42.94±2.38) % to (47.03±2.62) % in control group and from (43.51±2.45) to (52.94±3.09) in sudy group; the quality of life were increased from (42.08±7.44) points to (57.00±4.49) points in control group and (43.76±6.68) points to (69.42±8.03) points in sudy group; the GRACE score were increased from (152.10±14.52) points to (110.10±9.73) points in control group and (153.63±15.11) points to (81.71±10.21) points in sudy group, the difference were statistically significant (P < .05). All indicators in study group were better than those in control group at each time point after intervention (P < .05). Kaplan-Meier curve showed that the incidence of adverse cardiovascular events in the study group was lower than that in the control group within 3 months. Within 90 days of hospitalization, the incidence of adverse cardiovascular events were 28.81% in the control group, which was higher than 15.25% in the study group (P < .05). Kaplan-meier observation showed that the incidence of adverse cardiovascular events in control group was significantly higher than that in study group (χ2=5.586, P = .018).
Conclusions: The HOPE management model can effectively improve the cardiac function and quality of life of patients with myocardial infarction, and reduce GRACE scores and the incidence of in-hospital cardiovascular adverse events, which can as a comprehensive approach to improve clinical outcomes and enhance the quality of life for patients with myocardial infarction.