Immunostimulatory effects of thermal ablation: Challenges and future prospects

J Cancer Res Ther. 2024 Apr 1;20(2):531-539. doi: 10.4103/jcrt.jcrt_2484_23. Epub 2024 Apr 30.

Abstract

This literature explores the immunostimulatory effects of thermal ablation in the tumor microenvironment, elucidating the mechanisms such as immunogenic cell death, tumor-specific antigens, and damage-associated molecular patterns. Furthermore, it outlines critical issues associated with thermal ablation-induced immunostimulatory challenges and offers insights into future research avenues and potential therapeutic strategies.

Publication types

  • Review

MeSH terms

  • Animals
  • Antigens, Neoplasm / immunology
  • Humans
  • Hyperthermia, Induced / methods
  • Immunogenic Cell Death / drug effects
  • Neoplasms* / immunology
  • Neoplasms* / surgery
  • Tumor Microenvironment* / immunology

Substances

  • Antigens, Neoplasm