Terminal ileitis: a rare gastrointestinal manifestation of IgA vasculitis in a child

BMJ Case Rep. 2024 May 2;17(5):e240990. doi: 10.1136/bcr-2020-240990.

Abstract

A girl in middle childhood was referred to the paediatric surgical team with acute colicky abdominal pain and bile-stained vomiting. This was preceded by a viral illness. Investigations revealed raised inflammatory markers, and imaging of the abdomen demonstrated ileal and jejunal thickening. Concerns were raised regarding whether she had inflammatory bowel disease. Endoscopy revealed gastritis and duodenitis, and colonoscopy was unremarkable. Video capsule endoscopy demonstrated ulcers in the jejunum and ileum.On day 8 of admission, she developed a symmetrical purpuric rash over both ankles leading to the diagnosis of Henoch-Schonlein-related ileitis. Multidisciplinary team working led to appropriate management of the patient and avoided surgery. Video capsule endoscopy enabled visualisation of the small bowel. She was managed with 5 days of methylprednisolone followed by oral steroids. She made a good recovery with no sequelae. This case highlighted that terminal ileitis is a rare complication of IgA vasculitis with a good prognosis.

Keywords: Crohn's disease; Endoscopy; Paediatrics; Radiology; Vasculitis.

Publication types

  • Case Reports

MeSH terms

  • Capsule Endoscopy
  • Child
  • Female
  • Humans
  • IgA Vasculitis* / complications
  • IgA Vasculitis* / diagnosis
  • Ileitis* / complications
  • Ileitis* / diagnosis
  • Immunoglobulin A / immunology
  • Methylprednisolone / therapeutic use

Substances

  • Methylprednisolone
  • Immunoglobulin A