Peripheral nerve tumors

Handb Clin Neurol. 2024:201:251-271. doi: 10.1016/B978-0-323-90108-6.00016-8.


The chapter is focused on the neoplastic peripheral nerve lesions, which primarily involve "cranial and paraspinal nerves," as outlined in the CNS volume (WHO_Classification_of_Tumours_Editorial_Board, 2021). These include classic peripheral nerve sheath tumors such as schwannoma, neurofibroma, intraneural perineurioma, and malignant peripheral nerve sheath tumors, with their variants as well as new and more precisely defined entities, including hybrid nerve sheath tumors and malignant melanotic nerve sheath tumor (previously melanotic schwannoma).

Keywords: Malignant peripheral nerve sheath tumor; Neurofibroma; Perineurioma; Schwannoma.

Publication types

  • Review

MeSH terms

  • Humans
  • Nerve Sheath Neoplasms* / diagnosis
  • Nerve Sheath Neoplasms* / pathology
  • Neurilemmoma / diagnosis
  • Neurilemmoma / pathology
  • Neurofibroma / pathology
  • Peripheral Nervous System Neoplasms* / pathology