Histopathology of skin melanocytic lesions

Cesk Patol. 2024;60(1):12-34.

Abstract

Melanocytic lesions are instable tumors, the genome of which and its changes determinate their morphology and biological properties. Intermediate lesions share histomorphological features of both, nevi and melanoma. Melanocytomas represent a group of them separated on the basis of recent molecular-biological studies. The article summarizes benign, intermediate, malignant and combined melanocytic skin lesions and offers practical recommendations for diagnosis.

Keywords: classification; dermoscopy-histopathology correlations; genetic alterations; histopathology; intermediate lesions; melanocytic lesions; melanocytomas; practical recommendations for diagnosis.

Publication types

  • Review

MeSH terms

  • Humans
  • Melanoma* / diagnosis
  • Melanoma* / pathology
  • Nevus, Pigmented* / diagnosis
  • Nevus, Pigmented* / pathology
  • Skin Neoplasms* / diagnosis
  • Skin Neoplasms* / pathology