How Should We Manage Antimicrobial Resistance in Resource-Limited Settings?

AMA J Ethics. 2024 May 1;26(5):E373-379. doi: 10.1001/amajethics.2024.373.

Abstract

Patients living in low- and middle-income countries (LMICs) shoulder the greatest burden of infections caused by antimicrobial-resistant pathogens. Speedy access to appropriate broad-spectrum antimicrobials significantly improves health outcomes and reduces transmission of antimicrobial-resistant pathogens, but persons living in LMICs have compromised access to these antimicrobials. This article considers how inequities in microbiology diagnostics, antimicrobial access, and antimicrobial affordability influence outcomes for patients infected with antimicrobial-resistant pathogens who live in resource-limited settings.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Anti-Infective Agents / therapeutic use
  • Developing Countries*
  • Drug Resistance, Bacterial
  • Drug Resistance, Microbial
  • Health Resources*
  • Health Services Accessibility
  • Humans
  • Resource-Limited Settings

Substances

  • Anti-Bacterial Agents
  • Anti-Infective Agents