Managing Contact Dermatitis Without Patch Testing

J Allergy Clin Immunol Pract. 2024 Sep;12(9):2252-2259. doi: 10.1016/j.jaip.2024.04.047. Epub 2024 May 2.

Abstract

Allergic contact dermatitis (ACD) is a common skin condition caused by contact with an exogenous agent that elicits an inflammatory response. Patch testing (PT) is considered the gold standard for diagnosing ACD. Unfortunately, PT may not be available to some patients due to insurance and financial limitations, contributing to health care disparity and leaving patients with undiagnosed, incompletely managed dermatitis that can have further detrimental health and occupational effects. For other patients, PT is precluded by lack of availability of specialist/expert care, comorbid medications, or diffuse disease. This article will present a patient with ACD and will work through the differential diagnosis and share strategies for empiric avoidance of suspected/common triggers. The epidemiology of ACD with respect to race and ethnicity, considerations for affordability of hypoallergenic products, access to testing, and the need for future research are addressed in this article.

Keywords: Allergen avoidance; Allergic contact dermatitis; Ethnicity; Fragrances; Health care disparities; Patch testing; Preservatives; Race; Systemic contact dermatitis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Allergens / immunology
  • Dermatitis, Allergic Contact* / diagnosis
  • Dermatitis, Allergic Contact* / economics
  • Dermatitis, Allergic Contact* / epidemiology
  • Dermatitis, Allergic Contact* / therapy
  • Diagnosis, Differential
  • Humans
  • Patch Tests* / economics

Substances

  • Allergens