Persistent omphalomesenteric duct in an infant with trisomy 21

BMJ Case Rep. 2024 May 8;17(5):e259671. doi: 10.1136/bcr-2024-259671.


We present the case of a term newborn with trisomy 21 who presented to the paediatric emergency department with periumbilical flare and green-brown discharge from a clamped umbilical cord, initially suspected to be omphalitis. However, it was noticed later, that when the infant strained or cried, a thick, bubbling and offensive green-brown discharge came out of the clamped umbilical cord with umbilical flatus. An ultrasound abdomen and umbilical cord confirmed the presence of a persistent omphalomesenteric duct (POMD). He was then transferred to the paediatric surgical unit. There, he underwent a laparotomy and surgical resection of the POMD and was discharged home 2 days later.

Keywords: neonatal and paediatric intensive care; neonatal health; paediatric surgery; paediatrics.

Publication types

  • Case Reports

MeSH terms

  • Down Syndrome* / complications
  • Humans
  • Infant, Newborn
  • Laparotomy / methods
  • Male
  • Umbilical Cord / abnormalities
  • Umbilical Cord / diagnostic imaging
  • Umbilical Cord / pathology
  • Vitelline Duct* / abnormalities
  • Vitelline Duct* / diagnostic imaging