Early Detection and Interception of Lung Cancer

Hematol Oncol Clin North Am. 2024 Aug;38(4):755-770. doi: 10.1016/j.hoc.2024.03.004. Epub 2024 May 8.

Abstract

Recent advances in lung cancer treatment have led to dramatic improvements in 5-year survival rates. And yet, lung cancer remains the leading cause of cancer-related mortality, in large part, because it is often diagnosed at an advanced stage, when cure is no longer possible. Lung cancer screening (LCS) is essential for intercepting the disease at an earlier stage. Unfortunately, LCS has been poorly adopted in the United States, with less than 5% of eligible patients being screened nationally. This article will describe the data supporting LCS, the obstacles to LCS implementation, and the promising opportunities that lie ahead.

Keywords: Artificial intelligence; Cancer risk; Disparities; Early detection; Lung cancer; Lung cancer screening.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Early Detection of Cancer* / methods
  • Humans
  • Lung Neoplasms* / diagnosis
  • Lung Neoplasms* / therapy
  • Mass Screening / methods
  • United States / epidemiology