Design of an endoscopic OCT probe based on piezoelectric tube with quartered outside electrodes

Jinyuan Hu; Sujian Wu; Guohua Shi; Jinyu Fan; Haoyang Yu; Sixu Chen

doi:10.3389/fbioe.2024.1391630

Design of an endoscopic OCT probe based on piezoelectric tube with quartered outside electrodes

Front Bioeng Biotechnol. 2024 Apr 24:12:1391630. doi: 10.3389/fbioe.2024.1391630. eCollection 2024.

Authors

Jinyuan Hu^{1

2}, Sujian Wu^{1

2}, Guohua Shi^{1

2}, Jinyu Fan², Haoyang Yu^{1

2}, Sixu Chen^{1

2}

Affiliations

¹ School of Biomedical Engineering (Suzhou), Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
² Jiangsu Province Key Laboratory of Medical Optics, Suzhou Institute of Biomedical Engineering and Technology Chinese Academy of Science, Suzhou, China.

Abstract

Introduction: Optical coherence tomography (OCT) is a pivotal imaging modality in ophthalmology for real-time, in vivo visualization of retinal structures. To enhance the capability and safety of OCT, this study focuses on the development of a micro intraocular OCT probe. The demand for minimal invasiveness and precise imaging drives the need for advanced probe designs that can access tight and sensitive areas, such as the ocular sclera. Methods: A novel OCT probe was engineered using a piezoelectric tube with quartered electrodes to drive Lissajous scanning movements at the end of a single-mode fiber. This design allows the probe to enter the eyeball through a scleral opening. Structural innovation enables the outer diameter of the endoscopic OCT probe to be adjusted from 13G (2.41 mm) to 25G (0.51 mm), accommodating various imaging field sizes and ensuring compatibility with different scleral incisions. Results: The fabricated micro intraocular OCT probe successfully performed preliminary imaging experiments on in vivo fingers. The Lissajous scanning facilitated comprehensive coverage of the target area, enhancing the imaging capabilities. Discussion: The integration of a piezoelectric tube with quartered outside electrodes into the OCT probe design proved effective for achieving precise control over scanning movements and adaptability to different surgical needs. The design characteristics and practical applications demonstrated the probe's potential in clinical settings.

Keywords: endoscopic OCT probe; imaging in ophthalmology; optical coherence tomography (OCT); piezoelectric ceramic tube; single-mode fiber.

Grants and funding

The author(s) declare that financial support was received for the research, authorship, and/or publication of this article. This project was funded by: National Key R&D Program of China, Grant Nos.2021YFF0700503. CAS Project for Young Scientists in Basic Research, Grant Nos. YSBR-067. Jiangsu Science and Technology Plan Program, Grant Nos. BK20220263. National Key R&D Program of China, Grant Nos. 2022YFC2404201.