1 Senior Department of Otolaryngology Head and Neck Surgery, Chinese PLA General Hospital, Chinese PLA Medical School, Beijing 100853, China; State Key Laboratory of Hearing and Balance Science, Beijing 100853, China; National Clinical Research Center for Otolaryngologic Diseases, Beijing 100853, China; Key Laboratory of Hearing Science, Ministry of Education, Beijing 100853, China; Beijing Key Laboratory of Hearing Impairment Prevention and Treatment, Beijing 100853, China.