FDG PET/CT Findings of Primary Pulmonary Choriocarcinoma in a Postmenopausal Woman

Clin Nucl Med. 2024 Jul 1;49(7):698-700. doi: 10.1097/RLU.0000000000005272. Epub 2024 May 9.

Abstract

Choriocarcinomas usually occur in the genital tracts of reproductive-age women after a gestational event. Primary pulmonary choriocarcinoma is very rare. We describe FDG PET/CT findings of primary pulmonary choriocarcinoma with multiple intrapulmonary metastases in a postmenopausal woman with elevated serum beta human chorionic gonadotropin level. On FDG PET/CT, the large primary lung tumor showed intense FDG uptake (SUV max , 46), and the small intrapulmonary metastases showed variable FDG uptake (SUV max , 27). Primary pulmonary choriocarcinoma should be included in the differential diagnosis of FDG-avid pulmonary lesions with elevated serum beta human chorionic gonadotropin levels, including metastatic choriocarcinoma and lung cancer.

Publication types

  • Case Reports

MeSH terms

  • Choriocarcinoma* / diagnostic imaging
  • Choriocarcinoma* / pathology
  • Female
  • Fluorodeoxyglucose F18*
  • Humans
  • Lung Neoplasms* / diagnostic imaging
  • Middle Aged
  • Multimodal Imaging*
  • Positron Emission Tomography Computed Tomography*
  • Positron-Emission Tomography
  • Postmenopause*
  • Tomography, X-Ray Computed*

Substances

  • Fluorodeoxyglucose F18