Societal costs before and up to 1 year after the first fracture liaison service visit in patients requiring anti-osteoporosis treatments

Arch Osteoporos. 2024 May 13;19(1):36. doi: 10.1007/s11657-024-01390-7.

Abstract

This study aimed to estimate societal and healthcare costs incurred before and 1 year after the first fracture liaison services (FLS) visit and to explore differences in fracture type. All costs after 1 year significantly decreased compared to costs preceding the first visit. Fracture type did not significantly affect costs.

Introduction: Limited literature is available on resource utilization and costs of patients visiting fracture liaison services (FLS). This study aimed to estimate the societal and healthcare costs incurred by patients with a recent fracture requiring anti-osteoporosis medication before and 1 year after the first FLS visit and to explore differences according to fracture type.

Methods: Resource utilization was collected through a self-reported questionnaire with a 4-month recall on health resource utilization and productivity losses immediately following the first FLS visit, and 4 and 12 months later. Unit costs derived from the national Dutch guideline for economic evaluations were used to compute societal and healthcare costs. Linear mixed-effect models, adjusted for confounders, were used to analyze societal and healthcare costs over time as well as the effect of fracture type on societal and healthcare costs.

Results: A total of 126 patients from two Dutch FLS centers were included, of whom 72 sustained a major fracture (hip, vertebral, humerus, or radius). Societal costs in the 4 months prior to the first visit (€2911) were significantly higher compared to societal costs 4 months (€711, p-value = 0.009) and 12 months later (€581, p-value = 0.001). Fracture type did not have a significant effect on total societal or healthcare costs. All costs 12 months after the initial visit were numerically lower for major fractures compared to others.

Conclusion: Societal and healthcare costs in the year following the first FLS visit significantly decreased compared to those costs preceding the first visit.

Keywords: Anti-osteoporosis treatment; Fracture; Fracture liaison service; Longitudinal study; Osteoporosis; Societal costs.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Bone Density Conservation Agents* / economics
  • Bone Density Conservation Agents* / therapeutic use
  • Cost of Illness
  • Female
  • Health Care Costs* / statistics & numerical data
  • Humans
  • Male
  • Middle Aged
  • Netherlands
  • Osteoporosis* / drug therapy
  • Osteoporosis* / economics
  • Osteoporotic Fractures* / economics
  • Osteoporotic Fractures* / therapy

Substances

  • Bone Density Conservation Agents