Comparison of ICI 35868, etomidate and methohexitone for day-case anaesthesia

Br J Anaesth. 1985 Aug;57(8):732-5. doi: 10.1093/bja/57.8.732.

Abstract

The anaesthetic properties and side-effects of propofol 1.5 mg kg-1, etomidate 0.2 mg kg-1, and methohexitone 1.5 mg kg-1 were compared in 71 healthy female patients undergoing short gynaecological procedures. Propofol proved to be a safe and effective agent for induction and maintenance of anaesthesia and was associated with a lower incidence of side-effects than either etomidate or methohexitone.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Ambulatory Surgical Procedures
  • Anesthesia, Intravenous* / adverse effects
  • Anesthesia, Obstetrical / adverse effects
  • Anesthetics* / adverse effects
  • Attitude of Health Personnel
  • Etomidate* / adverse effects
  • Female
  • Humans
  • Imidazoles* / adverse effects
  • Methohexital* / adverse effects
  • Middle Aged
  • Patient Acceptance of Health Care
  • Phenols* / adverse effects
  • Pregnancy
  • Propofol
  • Time Factors

Substances

  • Anesthetics
  • Imidazoles
  • Phenols
  • Methohexital
  • Propofol
  • Etomidate