Prevention of post-ERCP complications

Best Pract Res Clin Gastroenterol. 2024 Mar:69:101906. doi: 10.1016/j.bpg.2024.101906. Epub 2024 Mar 22.

Abstract

Endoscopic retrograde cholangiopancreatography (ERCP) is a common endoscopic procedure which plays a key role in the management of diseases of the bile ducts and the pancreas. Despite ERCP being performed routinely since more than 4 decades, it is still related to a considerable rate of complications with post-ERCP pancreatitis being the most frequent one. Lately, endoscopic techniques have evolved, and numerous modalities have been developed to prevent or manage ERCP-related complications, especially PEP, such as the use of intra-rectal non-steroidal anti-inflammatory drugs (NSAIDs), insertion of prophylactic stents in the pancreatic duct (PD) or intravenous hyperhydration. Knowledge of the various risk factors and applying validated preventive methods are keys in providing a safe procedure and optimizing overall patient care.

Keywords: ERCP-related adverse events; Pancreatitis; Perforation; Quality indicators.

Publication types

  • Review

MeSH terms

  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Cholangiopancreatography, Endoscopic Retrograde* / adverse effects
  • Humans
  • Pancreatitis* / etiology
  • Pancreatitis* / prevention & control
  • Risk Factors
  • Stents

Substances

  • Anti-Inflammatory Agents, Non-Steroidal