Emergency Department Utilization by Pediatric Patients With Sickle Cell Disease in Basrah, Iraq

Ahmed S Marroof; Meaad K Hassan

doi:10.7759/cureus.58277

Emergency Department Utilization by Pediatric Patients With Sickle Cell Disease in Basrah, Iraq

Cureus. 2024 Apr 14;16(4):e58277. doi: 10.7759/cureus.58277. eCollection 2024 Apr.

Authors

Ahmed S Marroof¹, Meaad K Hassan²

Affiliations

¹ Department of Pediatrics, Al-Zubair general Hospital, Basrah Health Directorate, Basrah, IRQ.
² Department of Pediatrics, College of Medicine, University of Basrah, Basrah, IRQ.

Abstract

Background Patients with sickle cell disease (SCD) often present in the Emergency Department (ED) with acute and debilitating pain and other SCD-related complications. Objectives The objective is to analyze the causes of ED visits of pediatric patients with SCD, assess the burden of ED admission due to SCD in relation to other pediatric diseases, the treatment given, and the outcomes. Methods A prospective analytical study was conducted on children and adolescents with SCD, 1-14 years old who had been admitted to the ED at Basrah Maternity and Children Hospital over a six-month period. Patient's sociodemographic and clinical data, drug history, length of ED stay, complications, outcome, and readmissions were recorded. Results A total of 422 patients with SCD were admitted to ED during the study period representing 4.10% of the total admitted cases; 276(65.40%) of them were recruited in this study, and their mean age was 7.84 ±3.47 years. The main cause for ED admission was pain (73.91%), followed by infection (10.14%) and hemolytic crisis (6.15%). The mean duration of stay at ED was 6.11±1.87 hours. All admitted SCD patients had received analgesia; non-steroidal anti-inflammatory drugs (NSAIDs) were the commonest (80.4%), followed by acetaminophen (39.5%), and opioid narcotic (18.5%). Readmission within 30-days was reported in 82(29.71%) patients and was associated with the number of ED visits/last year (B=0.151, P=0.023), length of stay at ED (B=0.140, P=0.034) and severe disease (B=0.253, P<0.001). Conclusions Acute painful episodes were the main cause of ED admission. Although most patients with pain did receive NSAIDs, only a small percentage of them did receive opioids. About one-third of patients have been readmitted within 30 days, and readmission was associated with the number of ED visits/last year, disease severity, and length of ED stay. These findings can help in establishing local guidelines for managing such patients in the ED especially pain management.

Keywords: acute painful episodes; children and adolescents; emergency department; readmission; sickle cell disease.