Aspartic protease supplementation enhancing the performance, carcass characteristics, nutrient digestibility and economic viability, without changing blood parameters and salivary cortisol of pigs

Sci Rep. 2024 May 16;14(1):11238. doi: 10.1038/s41598-024-62006-1.

Abstract

Aiming to study the performance, carcass characteristics, nutrient digestibility, blood parameters, salivary cortisol levels, and economic viability of pigs administered aspartic protease, a total of 135 pigs were housed in pens in a randomized block design, divided into five treatments with nine replications. The experimental diets were positive control (PC), basic diet with a 5.0% reduction in protein and amino acid requirements; negative control (NC) with a 7.5% reduction in protein and amino acid requirements; NC + 100 g/mT of aspartic protease (NC100); NC + 150 g/mT of aspartic protease (NC150); and NC + 200 g/mT of neutral serine protease (NC200). The inclusion of protease, independently of the source and amount, increased the average daily weight gain (P < 0.05) of animals compared with the control treatments (PC and NC), improved feed conversion (P < 0.05) in early stages, and improved diet digestibility (P < 0.05) compared with the PC. Treatment with NC150 and NC200 resulted in greater carcass weights (P < 0.05) than treatment with the PC. NC100 led to a greater carcass yield than PC (P < 0.05), and NC150 resulted in a greater loin eye area than PC (P < 0.05). No differences (P > 0.05) in the blood parameters or salivary cortisol levels were found. Regarding economic viability, proteases increased the profitability, with NC150 leading to the best results. Thus, the use of aspartic proteases is recommended to improve performance and further facilitate pork production.

Keywords: Animal welfare; Enzymes; Hematological analyzes; Protein; Swine.

MeSH terms

  • Animal Feed* / analysis
  • Animal Nutritional Physiological Phenomena
  • Animals
  • Aspartic Acid Proteases* / metabolism
  • Diet / veterinary
  • Dietary Supplements*
  • Digestion* / physiology
  • Hydrocortisone* / blood
  • Hydrocortisone* / metabolism
  • Male
  • Saliva* / chemistry
  • Saliva* / metabolism
  • Swine