Instrumental activities of daily living function and cognitive status among Chinese older adults: a serial multiple mediation model

Front Public Health. 2024 May 2:12:1378979. doi: 10.3389/fpubh.2024.1378979. eCollection 2024.

Abstract

Objective: This study aimed to develop and validate a serial multiple mediation model to investigate the association between instrumental activities of daily living (IADL) function and cognitive status among older adults while exploring the underlying mechanisms.

Methods: This cross-sectional study involved 3,665 individuals aged 60 years and older who participated in the China Health and Retirement Longitudinal Survey (CHARLS). A serial multiple mediation model was utilized to explore the direct and indirect relationship between IADL function and cognitive status and whether sleep duration, social engagement, and depressive symptoms mediated this relationship.

Results: Decreased IADL function was associated with worse cognitive status [effect = -0.620, 95% CI: (-0.692, -0.540)]. Sleep duration, social participation (SP), and depressive symptoms all acted as mediators in the relationship between IADL function and cognitive status.

Conclusion: This study found both direct and indirect associations between IADL function and cognitive status, providing new insights into the effective prevention and intervention of cognitive decline among older adults.

Keywords: IADL; cognitive status; depressive symptoms; sleep duration; social participation.

MeSH terms

  • Activities of Daily Living*
  • Aged
  • Aged, 80 and over
  • China
  • Cognition* / physiology
  • Cognitive Dysfunction
  • Cross-Sectional Studies
  • Depression* / epidemiology
  • East Asian People
  • Female
  • Humans
  • Longitudinal Studies
  • Male
  • Mediation Analysis
  • Middle Aged
  • Social Participation

Grants and funding

The author(s) declare that no financial support was received for the research, authorship, and/or publication of this article.