The diagnosis and misdiagnosis of Sjögren disease

Intern Med J. 2024 May;54(5):833-835. doi: 10.1111/imj.16395.


Although one of the most common systemic autoimmune disorders, Sjögren disease (SjD) may be overlooked in patients presenting with non-specific symptoms or no complaints of sicca symptoms. SjD is not a condition to be missed as patients could present with serious extra-glandular manifestations, including lymphomas. In this article, we discuss the diagnostic pitfalls of this disorder and encourage physicians to consider carefully the 'non-textbook' presentations.

Keywords: Sjögren disease; autoimmunity; diagnosis; immunology; rheumatology.

MeSH terms

  • Diagnosis, Differential
  • Diagnostic Errors*
  • Humans
  • Sjogren's Syndrome* / diagnosis