Cannabis legalization and hospitalizations in Alberta: Interrupted time series analysis by age and sex

J Addict Dis. 2025 Apr-Jun;43(2):194-197. doi: 10.1080/10550887.2024.2355370. Epub 2024 May 19.

Abstract

Objectives: Recent research has focused on the effects of legalization on cannabis-related emergency department visits, but the considerable healthcare costs of cannabis-related hospitalizations merit attention. We will examine the association between recreational cannabis legalization and cannabis-related hospitalizations.

Methods: A cohort of 3,493,864 adults from Alberta was examined (October 2015-May 2021) over three periods: pre-legalization, post-legalization of flowers and herbs (phase one), and post-legalization of edibles, extracts, and topicals (phase two). Interrupted time series analyses were used to detect changes.

Results: The study found an increase in hospitalization rates among younger adults (18-24) before legalization, yet no increased risk was associated with cannabis legalization, for either younger (18-24) or older adults (25+).

Conclusions: Clinicians should be aware of the increased risk in younger groups and may benefit from early identification and intervention strategies, including screening and brief interventions in primary care settings.

Keywords: Canada; Cannabis; hospitalizations.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Alberta / epidemiology
  • Cannabis
  • Female
  • Hospitalization* / statistics & numerical data
  • Humans
  • Interrupted Time Series Analysis*
  • Legislation, Drug
  • Male
  • Middle Aged
  • Sex Factors
  • Young Adult