Progress in triacylglycerol isomer detection in milk lipids

Huiru Cao; Qian Liu; Yan Liu; Junying Zhao; Weicang Qiao; Yuru Wang; Yan Liu; Lijun Chen

doi:10.1016/j.fochx.2024.101433

Progress in triacylglycerol isomer detection in milk lipids

Food Chem X. 2024 May 3:22:101433. doi: 10.1016/j.fochx.2024.101433. eCollection 2024 Jun 30.

Authors

Huiru Cao^{1

2

3}, Qian Liu^{1

2

3}, Yan Liu^{2

3}, Junying Zhao^{2

3}, Weicang Qiao^{2

3}, Yuru Wang^{1

2

3}, Yan Liu^{2

3}, Lijun Chen^{1

2

3}

Affiliations

¹ Key Laboratory of Dairy Science, Ministry of Education, Food Science College, Northeast Agricultural University, Harbin 150030, China.
² National Engineering Research Center of Dairy Health for Maternal and Child, Beijing Sanyuan Foods Co. Ltd., Beijing 100163, China.
³ Beijing Engineering Research Center of Dairy, Beijing Technical Innovation Center of Human Milk Research, Beijing Sanyuan Foods Co. Ltd., Beijing 100163, China.

Abstract

In triacylglycerols (TAGs), position differences of fatty acids on the glycerol skeleton produce various TAG isomers. These TAG isomers have different pathways of digestion, absorption, and utilization in infants, thereby affecting TAG nutritional properties of TAGs. Here, we review the progress of research on methods for detecting TAG isomers, and identify direction and thought for improving these methods, including novel chromatographic combinations, perfect algorithm, and improved equipment. The ensuing optimization of these methods is expected to provide robust guarantee for the gradual improvement of milk-derived TAG isomer detection, and is an important prerequisite for infant formula to mimic the structured lipids of human milk.

Keywords: Chromatogram; Ion fragment; Isomers; Triacylglycerol.

Publication types

Review