Pseudomembranous colitis following low dose trimethoprim-sulfamethoxazole

J Urol. 1985 Dec;134(6):1218-9. doi: 10.1016/s0022-5347(17)47694-4.

Abstract

A 94-year-old man had pseudomembranous colitis while taking low dose trimethoprim-sulfamethoxazole for recurrent urinary tract infection. The suppressive effect of low dose trimethoprim-sulfamethoxazole on normal colonic flora appeared to be a factor in the development of pseudomembranous colitis in this patient.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Anti-Infective Agents, Urinary / adverse effects*
  • Anti-Infective Agents, Urinary / therapeutic use
  • Drug Combinations / adverse effects
  • Drug Combinations / therapeutic use
  • Enterocolitis, Pseudomembranous / chemically induced*
  • Humans
  • Male
  • Sulfamethoxazole / adverse effects*
  • Sulfamethoxazole / therapeutic use
  • Trimethoprim / adverse effects*
  • Trimethoprim / therapeutic use
  • Trimethoprim, Sulfamethoxazole Drug Combination
  • Urinary Tract Infections / prevention & control

Substances

  • Anti-Infective Agents, Urinary
  • Drug Combinations
  • Trimethoprim, Sulfamethoxazole Drug Combination
  • Trimethoprim
  • Sulfamethoxazole