Effects of Omega-3 fatty acids supplementation and resistance training on skeletal muscle

Clin Nutr ESPEN. 2024 Jun:61:189-196. doi: 10.1016/j.clnesp.2024.03.019. Epub 2024 Mar 21.

Abstract

Background & aims: The aim of this study was to investigate the omega-3 fatty acids supplementation, and resistance training on muscle strength and mass.

Methods: A review was conducted by searching relevant randomized controlled trials investigating the effects of omega-3 fatty acids supplementation and resistance training on skeletal muscle strength and mass. Three experts independently performed a thorough examination of the literature database and conducted the systematic review and meta-analysis.

Results: Four studies were ultimately included in the systematic review after screening. The results of the meta-analysis revealed that the supplementation of omega-3 fatty acids and resistance training significantly improved muscle strength compared to the placebo-controlled group. However, no significant effects were observed in the effect for muscle mass.

Conclusions: The interventions of omega-3 fatty acids supplementation and resistance training show promise as a countermeasure against muscular dysfunction. While further research is warranted to investigate its effects on skeletal muscle mass, the findings of this study hold implications for maintaining and/or improving the quality of life to elderly people.

Keywords: Ergogenic aid; Muscle strength; Sarcopenia; Sports nutrition; Supplementation.

Publication types

  • Systematic Review
  • Meta-Analysis

MeSH terms

  • Dietary Supplements*
  • Fatty Acids, Omega-3* / administration & dosage
  • Fatty Acids, Omega-3* / pharmacology
  • Humans
  • Muscle Strength* / drug effects
  • Muscle, Skeletal* / drug effects
  • Muscle, Skeletal* / physiology
  • Quality of Life
  • Randomized Controlled Trials as Topic
  • Resistance Training*

Substances

  • Fatty Acids, Omega-3