Perioperative Evaluation and Management of Children with Osteoporosis and Low Bone Mineral Density

Abstract

As medical and surgical treatment options for children with osteoporosis expand, multidisciplinary strategies for bone health optimization become more important. Each patient's bone mineral density and fracture history should be interpreted in context. Off-label bisphosphonate use is a standard pharmacologic intervention for children with osteoporosis for optimal bone accrual. It is possible to continue this therapy perioperatively under certain circumstances. The rare side effects (osteonecrosis of the jaw and atypical femur fractures) seem less common in children. Physical therapy, vitamin D supplementation, and other interventions are also important tools for optimal bone health perioperatively and for satisfactory surgical outcomes.

Keywords: Bisphosphonate; Bone heath optimization; Osteogenesis imperfecta; Osteoporosis; Osteotomy; Pediatric; Perioperative.