Serological and clinical remission in systemic lupus erythematosus

J Rheumatol. 1985 Oct;12(5):916-8.


The frequency of a combined clinical and serological remission in patients with systemic lupus erythematosus (SLE) was examined. Thirteen (4%) of 305 patients had both a seroconversion from a positive to a negative ANA and became asymptomatic in respect to their SLE. These remissions lasted from 6 months to 13 years. It is not clear what role, if any, therapy played in these remissions. Nevertheless, these remissions provided hope for the patients and their physicians.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Antibodies, Antinuclear / analysis*
  • Child
  • Female
  • Humans
  • Lupus Erythematosus, Systemic / immunology*
  • Middle Aged
  • Remission, Spontaneous
  • Time Factors


  • Antibodies, Antinuclear