Tenofovir induced Fanconi syndrome in a middle age African female from Kenya, East Africa: Case report and brief literature review

Fredrick Odhiambo; Shallot Nareeba; Grace Mwangeka; Ann Njambi; Vashti Nyakebati

doi:10.1002/ccr3.8889

Tenofovir induced Fanconi syndrome in a middle age African female from Kenya, East Africa: Case report and brief literature review

Clin Case Rep. 2024 May 24;12(6):e8889. doi: 10.1002/ccr3.8889. eCollection 2024 Jun.

Authors

Fredrick Odhiambo¹, Shallot Nareeba¹, Grace Mwangeka¹, Ann Njambi¹, Vashti Nyakebati¹

Affiliation

¹ Maua Methodist Hospital Meru Kenya.

Abstract

This case presentation highlights the need to routinely monitor renal function in patients on Tenofovir Disoproxil Fumarate (TDF) due to its side effect of proximal tubule dysfunction.

Abstract: This is a case presentation of a 50-year-old African female who had been on a Tenofovir based regimen for 12 years and developed Fanconi syndrome. She recovered after discontinuation of the Tenofovir Disoproxil Fumarate (TDF).

Keywords: Fanconi syndrome; antiretroviral therapy; drug induced nephrotoxicity; tenofovir.

Publication types

Case Reports