Antitracheobronchospastic interaction in vitro and in vivo between salbutamol and flunisolide

E Lampa; A Filippelli; A Pirozzi; C Matera; E Marmo; M Fano; D Montagna; V Bernareggi

Antitracheobronchospastic interaction in vitro and in vivo between salbutamol and flunisolide

Drugs Exp Clin Res. 1985;11(9):653-8.

Authors

E Lampa¹, A Filippelli, A Pirozzi, C Matera, E Marmo, M Fano, D Montagna, V Bernareggi

Affiliation

¹ Department of Pharmacology and Toxicology, First Faculty of Medicine and Surgery, University of Naples, Italy.

PMID: 3880052

Abstract

Salbutamol and flunisolide, when administered in association, are able to potentiate their effects both in vitro and in vivo on relaxation of the tracheobronchial smooth muscle of the guinea-pig.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acetylcholine / pharmacology
Albuterol / pharmacology*
Animals
Anti-Inflammatory Agents / pharmacology*
Bronchi / drug effects*
Bronchi / physiopathology
Bronchial Spasm / physiopathology
Bronchial Spasm / prevention & control
Dose-Response Relationship, Drug
Drug Interactions
Fluocinolone Acetonide / analogs & derivatives*
Fluocinolone Acetonide / pharmacology
Guinea Pigs
In Vitro Techniques
Trachea / drug effects*
Trachea / physiopathology

Substances

Anti-Inflammatory Agents
Fluocinolone Acetonide
flunisolide
Acetylcholine
Albuterol