Comparison of the analgesic efficacy of flurbiprofen and aspirin for postsurgical dental pain

J Oral Maxillofac Surg. 1985 Feb;43(2):106-9. doi: 10.1016/0278-2391(85)90056-4.

Abstract

The analgesic efficacy of flurbiprofen 25 mg and 50 mg compared with aspirin 650 mg and placebo (lactose) was evaluated. Subjects were 164 dental outpatients undergoing the surgical removal of impacted teeth. Each subject received a single dose of study medication and was evaluated hourly for six hours. Aspirin was superior to placebo in all measures of analgesic efficacy, and both dosages of flurbiprofen were superior to aspirin.

Publication types

  • Clinical Trial
  • Comparative Study
  • Controlled Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aspirin / administration & dosage
  • Aspirin / adverse effects
  • Aspirin / therapeutic use*
  • Clinical Trials as Topic
  • Dose-Response Relationship, Drug
  • Double-Blind Method
  • Drug Administration Schedule
  • Female
  • Flurbiprofen / administration & dosage
  • Flurbiprofen / adverse effects
  • Flurbiprofen / therapeutic use*
  • Humans
  • Male
  • Pain, Postoperative / drug therapy*
  • Placebos
  • Propionates / therapeutic use*
  • Time Factors
  • Tooth Extraction

Substances

  • Placebos
  • Propionates
  • Flurbiprofen
  • Aspirin