Venom Hypersensitivity

Med Clin North Am. 2024 Jul;108(4):757-776. doi: 10.1016/j.mcna.2023.08.008.

Abstract

Stinging insects are a frequent cause of local and systemic hypersensitivity reactions, including anaphylaxis. For those with a history of life-threatening anaphylaxis, venom immunotherapy is effective, safe, and can be life-saving. Arachnids are a much less common source of envenomation through bites or stings and are less likely to cause a hypersensitivity reaction. However, recognizing the clinical manifestations when they do present is important for accurate diagnosis and treatment, and, when indicated, consideration of other diagnoses.

Keywords: Anaphylaxis; Imported fire ant; Spider bite; Stinging hymenoptera; Stinging insect; Venom hypersensitivity; Venom immunotherapy; Widow spider.

Publication types

  • Review

MeSH terms

  • Anaphylaxis* / diagnosis
  • Anaphylaxis* / etiology
  • Anaphylaxis* / therapy
  • Animals
  • Arthropod Venoms / adverse effects
  • Arthropod Venoms / immunology
  • Desensitization, Immunologic / methods
  • Humans
  • Hypersensitivity / diagnosis
  • Hypersensitivity / therapy
  • Insect Bites and Stings* / complications
  • Venom Hypersensitivity

Substances

  • Arthropod Venoms