Antiepithelial autoantibodies associated with the feline eosinophilic granuloma complex

Am J Vet Res. 1985 Jan;46(1):263-5.

Abstract

A retrospective study of banked sera from 19 cats with the eosinophilic granuloma complex revealed that 68% of affected cats had circulating antibodies to components of normal cat epithelium. Seemingly, the eosinophilic granuloma complex of cats may be an autoimmune disease; however, epidermal damage caused by the eosinophilic granuloma complex may release altered self-antigens to which the cat's immune system responds.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Autoantibodies / analysis*
  • Cat Diseases / immunology*
  • Cats
  • Eosinophilic Granuloma / veterinary*
  • Epithelium / immunology
  • Fluorescent Antibody Technique

Substances

  • Autoantibodies