Modifying lignin: A promising strategy for plant disease control

Int J Biol Macromol. 2024 Jun;271(Pt 2):132696. doi: 10.1016/j.ijbiomac.2024.132696. Epub 2024 May 31.

Abstract

Lignin is a complex polymer found in the cell walls of plants, providing structural support and protection against pathogens. By modifying lignin composition and structure, scientists aim to optimize plant defense responses and increase resistance to pathogens. This can be achieved through various genetic engineering techniques which involve manipulating the genes responsible for lignin synthesis. By either up regulating or down regulating specific genes, researchers can alter the lignin content, composition, or distribution in plant tissues. Reducing lignin content in specific tissues like leaves can improve the effectiveness of defense mechanisms by allowing for better penetration of antimicrobial compounds. Overall, Lignin modification through techniques has shown promising results in enhancing various plants resistance against pathogens. Furthermore, lignin modification can have additional benefits beyond pathogen resistance. It can improve biomass processing for biofuel production by reducing lignin recalcitrance, making the extraction of sugars from cellulose more efficient. The complexity of lignin biosynthesis and its interactions with other plant components make it a challenging target for modification. Additionally, the potential environmental impact and regulatory considerations associated with genetically modified organisms (GMOs) require careful evaluation. Ongoing research aims to further optimize this approach and develop sustainable solutions for crop protection.

Keywords: Lignin engineering; Lignin modification; Pathogens; Plant's defense; Polymer.

Publication types

  • Review

MeSH terms

  • Biomass
  • Disease Resistance / genetics
  • Genetic Engineering
  • Lignin* / chemistry
  • Lignin* / metabolism
  • Plant Diseases* / genetics
  • Plant Diseases* / microbiology
  • Plant Diseases* / prevention & control
  • Plants / genetics
  • Plants / metabolism
  • Plants, Genetically Modified

Substances

  • Lignin