Ten-minute detection of group A streptococci in pediatric throat swabs

J Clin Microbiol. 1985 Feb;21(2):258-9. doi: 10.1128/jcm.21.2.258-259.1985.

Abstract

A 10-min latex agglutination test kit, Culturette Brand Ten-Minute Group A Strep ID (Marion Scientific, Div. of Marion Laboratories, Inc., Kansas City, Mo.), was assessed for the rapid detection of group A beta-hemolytic streptococcus directly from a throat swab. Four hundred and thirty-five throat swab specimens from children with suspected group A streptococcal infection were tested by the Ten-Minute Group A Strep ID and by concurrent conventional culture. The strep test was effective in detecting group A streptococcal infection; 90% (63/70) of culture-positive specimens gave positive latex tests. The specificity of the test was 99.2% (362/365). The predictive values were 95.5% for positives and 98.1% for negatives. Overall agreement with culture was 98% (425/435). This test offers a sensitive and specific method for the early detection of group A beta-hemolytic streptococci in throat swabs of children and would be most useful in a hospital laboratory or pediatrician's office.

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Humans
  • Infant
  • Latex Fixation Tests
  • Pharynx / microbiology*
  • Reagent Kits, Diagnostic
  • Streptococcal Infections / diagnosis
  • Streptococcus pyogenes / isolation & purification*
  • Time Factors

Substances

  • Reagent Kits, Diagnostic